Pathogen & Host Interaction in Disease Conditions

Publications & Structure Gallery

Dong Y*, Bonin J*, Devant P*, Liang Z*, Sever AI.M., Mintseris J, Aramini JM, Gygi SP,Kagan JC, Kay LE, Wu H. Structural transitions enable IL-18 maturation and signaling.Immunity (2024).

Devant P*, Dong Y*, Mintseris J, Ma W, Gygi SP, Wu H, Kagan JC. Structural insightsinto cytokine cleavage by inflammatory caspase-4. Nature (2023).

Dong Y*, Pi X*, Bartels-Burgahn F, D Saltukoglu, Liang Z, Yang J, Alt F. W, Reth M, WuH, Structural principles of B-cell antigen receptor assembly. Nature (2022).

Fontana P*, Dong Y*, Pi X*, Tong AB*, Hecksel CW, Wang L, Fu TM, Bustamante C,Wu H. Structure of the cytoplasmic ring of the nuclear pore complex by integrative cryoEM and AlphaFold prediction. Science (2022).

Xia S*, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu T-M, JacobsonMP, Greka A, Lieberman J, Ruan J, Wu H. Gasdermin D pore structure revealspreferential release of mature interleukin-1. Nature (2021)

Yuan Y, Cao C, Wen M, Li M, Dong Y, Wu L, Wu J, Cui T, Li D, Chou JJ, OuYang B.Structural Characterization of the N-Terminal Domain of the Dictyosteliumdiscoideum Mitochondrial Calcium Uniporter. ACS Omega (2020)

OuYang B, Dong Y. Chou J.J. Structural and Functional Properties of Viral MembraneProteins. Advances in Membrane Proteins (2018)

Oxenoid K*, Dong Y*, Cao C*, Cui T*, Sancak Y, Markhard AL, Grabarek Z, Kong L, LiuZ, Ouyang B, Cong Y, Mootha VK, Chou JJ. Architecture of the mitochondrial calciumuniporter. Nature (2016).